Classically, fibrous dysplasia lesions are intramedullary, expansile, and well defined lucent lesion in the diaphysis or metaphysic ("long lesion in long bone"). Although endosteal scalloping may be present, a smooth cortical contour is always maintained (absence of periosteal reaction). Lesions show varying degrees of hazy density with a ground-glass quality, although some may appear almost completely radiolucent or sclerotic. The lesion may be surrounded by a layer of thick, sclerotic reactive bone termed a rind. The classic rind is most commonly seen in proximal femur.

Frontal femur

Lateral femur

Ax CT

Cor CT ref
52 yo with lytic lesion in proximal femur
Classically, fibrous dysplasia lesions are intramedullary, expansile, and well defined lucent lesion in the diaphysis or metaphysic ("long lesion in long bone"). Although endosteal scalloping may be present, a smooth cortical contour is always maintained (absence of periosteal reaction). Lesions show varying degrees of hazy density with a ground-glass quality, although some may appear almost completely radiolucent or sclerotic. The lesion may be surrounded by a layer of thick, sclerotic reactive bone termed a rind. The classic rind is most commonly seen in proximal femur. This sclerotic margin can be of variable thickness and may be interrupted or incomplete. Even without this reactive sclenotic margin, the lesion is typically sharply marginated.
Suggested Reading:
MJ Kransdorf, RP Moser, Jr, and FW Gilkey. Fibrous dysplasia. RadioGraphics 1990; 10: 519.
R Kumar, JE Madewell, MM Lindell, and LE Swischuk. Fibrous lesions of bones. RadioGraphics 1990; 10: 237.
